HOWARD HUGHES MEDICAL INSTITUTE | 2011 ANNUAL REPORT

HHMI Investigators

Howard Hughes Medical Institute investigators conduct research in Institute laboratories at host institutions nationwide in concert with associated hospitals and medical schools. For information on HHMI investigators active after August 31, 2011, visit www.hhmi.org.

Arizona

University of Arizona
Roy Parker, Ph.D.

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California

California Institute of Technology
David J. Anderson, Ph.D.
Pamela J. Björkman, Ph.D.
David C. Chan, M.D., Ph.D.
Raymond J. Deshaies, Ph.D.
Michael B. Elowitz, Ph.D.
Linda C. Hsieh-Wilson, Ph.D.
Grant J. Jensen, Ph.D.
Dianne K. Newman, Ph.D.
Douglas C. Rees, Ph.D.
Paul W. Sternberg, Ph.D.
Salk Institute for Biological Studies
Joanne Chory, Ph.D.
Andrew Dillin, Ph.D.
Sascha du Lac, Ph.D.
Ronald M. Evans, Ph.D.
Joseph P. Noel, Ph.D.
Samuel L. Pfaff, Ph.D.
Terrence J. Sejnowski, Ph.D.
Stanford University
Philip A. Beachy, Ph.D.
Patrick O. Brown, M.D., Ph.D.
Axel T. Brunger, Ph.D.
Gerald R. Crabtree, M.D.
Mark M. Davis, Ph.D.
K. Christopher Garcia, Ph.D.
Seung K. Kim, M.D., Ph.D.
David M. Kingsley, Ph.D.
Mark A. Krasnow, M.D., Ph.D.
Liqun Luo, Ph.D.
William T. Newsome, Ph.D.
Roel Nusse, Ph.D.
Stephen R. Quake, D.Phil.
Mark J. Schnitzer, Ph.D.
Matthew P. Scott, Ph.D.
Kang Shen, Ph.D.
Thomas C. Südhof, M.D.
Julie A. Theriot, Ph.D.
University of California, Berkeley
Carolyn R. Bertozzi, Ph.D.
Carlos Bustamante, Ph.D.
Christopher J. Chang, Ph.D.
Yang Dan, Ph.D.
Abby F. Dernburg, Ph.D.
Jennifer A. Doudna, Ph.D.
Michael B. Eisen, Ph.D.
Jay T. Groves, Ph.D.
Douglas E. Koshland, Ph.D.
John Kuriyan, Ph.D.
Barbara J. Meyer, Ph.D.
Eva Nogales, Ph.D.
Randy W. Schekman, Ph.D.
University of California, Los Angeles
Douglas L. Black, Ph.D.
Edward M. De Robertis, M.D., Ph.D.
David Eisenberg, D.Phil.
Steven E. Jacobsen, Ph.D.
Peter Tontonoz, M.D., Ph.D.
Owen N. Witte, M.D.
S. Lawrence Zipursky, Ph.D.
University of California, San Diego
Steven F. Dowdy, Ph.D.
Susan Ferro-Novick, Ph.D.
Joseph G. Gleeson, M.D.
Lawrence S.B. Goldstein, Ph.D.
Yishi Jin, Ph.D.
J. Andrew McCammon, Ph.D.
Michael G. Rosenfeld, M.D.
Massimo Scanziani, Ph.D.
Susan S. Taylor, Ph.D.
Roger Y. Tsien, Ph.D.
University of California, San Francisco
David A. Agard, Ph.D.
Jason G. Cyster, Ph.D.
Joseph L. DeRisi, Ph.D.
Donald Ganem, M.D.
Lily Y. Jan, Ph.D.
Yuh Nung Jan, Ph.D.
Wendell A. Lim, Ph.D.
Stephen G. Lisberger, Ph.D.
Richard M. Locksley, M.D.
Louis J. Ptáček, M.D.
David H. Rowitch, M.D., Ph.D.
Kevan M. Shokat, Ph.D.
Jack Taunton, Ph.D.
Ronald D. Vale, Ph.D.
Peter Walter, Ph.D.
Arthur Weiss, M.D., Ph.D.
Jonathan S. Weissman, Ph.D.
University of California, Santa Cruz
David Haussler, Ph.D.

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Colorado

Colorado State University
Karolin Luger, Ph.D.
National Jewish Health
John W. Kappler, Ph.D.
Philippa Marrack, Ph.D.
University of Colorado
Natalie G. Ahn, Ph.D.
Kristi S. Anseth, Ph.D.
Thomas R. Cech, Ph.D.
Min Han, Ph.D.
James L. Maller, Ph.D.
Lee A. Niswander, Ph.D.

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Connecticut

Yale University
Ronald R. Breaker, Ph.D.
Peter Cresswell, Ph.D.
Pietro De Camilli, M.D.
Erol Fikrig, M.D.
Richard A. Flavell, Ph.D.
Eduardo A. Groisman, Ph.D.
Arthur L. Horwich, M.D.
Christine Jacobs-Wagner, Ph.D.
Richard P. Lifton, M.D., Ph.D.
Ruslan M. Medzhitov, Ph.D.
Anna Marie Pyle, Ph.D.
G. Shirleen Roeder, Ph.D.
David G. Schatz, Ph.D.
Gerald I. Shulman, M.D., Ph.D.
Joan A. Steitz, Ph.D.
Thomas A. Steitz, Ph.D.
Tian Xu, Ph.D.

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Georgia

Emory University
Kerry J. Ressler, M.D., Ph.D.

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Illinois

Northwestern University
Robert A. Lamb, Ph.D., Sc.D.
The University of Chicago
Albert Bendelac, M.D., Ph.D.
Bruce T. Lahn, Ph.D.
Milan Mrksich, Ph.D.
Jonathan K. Pritchard, Ph.D.
University of Illinois at Urbana-Champaign
Taekjip Ha, Ph.D.
Phillip A. Newmark, Ph.D.
Wilfred A. van der Donk, Ph.D.

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Indiana

Purdue University
Jue Chen, Ph.D.

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Iowa

The University of Iowa
Kevin P. Campbell, Ph.D.
Val C. Sheffield, M.D., Ph.D.
Edwin M. Stone, M.D., Ph.D.
Michael J. Welsh, M.D.

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Maine

The Jackson Laboratory
Susan L. Ackerman, Ph.D.
Simon W.M. John, Ph.D.

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Maryland

Carnegie Institution of Washington
Allan C. Spradling, Ph.D.
Yixian Zheng, Ph.D.
The Johns Hopkins University
William R. Bishai, M.D., Ph.D.
Nancy L. Craig, Ph.D.
Harry C. Dietz, M.D.
David D. Ginty, Ph.D.
Rachel Green, Ph.D.
Richard L. Huganir, Ph.D.
Alex L. Kolodkin, Ph.D.
Jeremy Nathans, M.D., Ph.D.
Duojia Pan, Ph.D.
Geraldine Seydoux, Ph.D.
Robert F. Siliciano, M.D., Ph.D.
Bert Vogelstein, M.D.
Cynthia Wolberger, Ph.D.
University of Maryland, Baltimore
Christopher V. Plowe, M.D.
University of Maryland, Baltimore County
Michael F. Summers, Ph.D.

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Massachusetts

Beth Israel Deaconess Medical Center
S. Ananth Karumanchi, M.D.
Boston University
James J. Collins, Ph.D.
Brandeis University
Nikolaus Grigorieff, Ph.D.
Dorothee Kern, Ph.D.
Christopher Miller, Ph.D.
Michael Rosbash, Ph.D.
Brigham and Women’s Hospital
Stephen J. Elledge, Ph.D.
Christine E. Seidman, M.D.
Matthew K. Waldor, M.D., Ph.D.
Children’s Hospital Boston
Frederick W. Alt, Ph.D.
David E. Clapham, M.D., Ph.D.
George Q. Daley, M.D., Ph.D.
Elizabeth C. Engle, M.D.
Stuart H. Orkin, M.D.
Christopher A. Walsh, M.D., Ph.D.
Matthew L. Warman, M.D.
Morris F. White, Ph.D.
Leonard I. Zon, M.D.
Dana-Farber Cancer Institute
Todd R. Golub, M.D.
William G. Kaelin Jr., M.D.
David Pellman, M.D.
Harvard College, Faculty of Arts and Sciences
Randy L. Buckner, Ph.D.
Catherine Dulac, Ph.D.
David R. Liu, Ph.D.
Douglas A. Melton, Ph.D.
Erin K. O’Shea, Ph.D.
Stuart L. Schreiber, Ph.D.
Xiaowei Zhuang, Ph.D.
Harvard Medical School
Constance L. Cepko, Ph.D.
David P. Corey, Ph.D.
Stephen C. Harrison, Ph.D.
John H.R. Maunsell, Ph.D.
Danesh Moazed, Ph.D.
Norbert Perrimon, Ph.D.
Tom A. Rapoport, Ph.D.
Bernardo L. Sabatini, M.D., Ph.D.
Thomas Walz, Ph.D.
Massachusetts General Hospital
Daniel A. Haber, M.D., Ph.D.
Jeannie T. Lee, M.D., Ph.D.
Jack W. Szostak, Ph.D.
Bruce D. Walker, M.D.
Massachusetts Institute of Technology
Angelika Amon, Ph.D.
Tania A. Baker, Ph.D.
David P. Bartel, Ph.D.
Mark F. Bear, Ph.D.
Stephen P. Bell, Ph.D.
Sangeeta N. Bhatia, M.D., Ph.D.
Catherine L. Drennan, Ph.D.
H. Robert Horvitz, Ph.D.
Richard O. Hynes, Ph.D.
Darrell J. Irvine, Ph.D.
Tyler Jacks, Ph.D.
Susan Lindquist, Ph.D.
David C. Page, M.D.
David M. Sabatini, M.D., Ph.D.
H. Sebastian Seung, Ph.D.
Li-Huei Tsai, Ph.D.
Tufts University
Andrew Camilli, Ph.D.
Ralph R. Isberg, Ph.D.
University of Massachusetts
Roger J. Davis, Ph.D.
Michael R. Green, M.D., Ph.D.
Craig C. Mello, Ph.D.
Melissa J. Moore, Ph.D.
Phillip D. Zamore, Ph.D.

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Michigan

University of Michigan
James C.A. Bardwell, Ph.D.
Arul M. Chinnaiyan, M.D., Ph.D.
David Ginsburg, M.D.
Friedhelm Hildebrandt, M.D.
John V. Moran, Ph.D.
Sean J. Morrison, Ph.D.
Mercedes Pascual, Ph.D.

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Missouri

Stowers Institute for Medical Research
Alejandro Sánchez Alvarado, Ph.D.
Washington University in St. Louis
Daniel E. Goldberg, M.D., Ph.D.
Kenneth M. Murphy, M.D., Ph.D.
Helen Piwnica-Worms, Ph.D.
Andrey S. Shaw, M.D.
Wayne M. Yokoyama, M.D.

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New Jersey

Princeton University
Bonnie L. Bassler, Ph.D.
Carlos D. Brody, Ph.D.
Leonid Kruglyak, Ph.D.
Trudi Schüpbach, Ph.D.
David L. Stern, Ph.D.
Eric F. Wieschaus, Ph.D.
Rutgers, The State University of New Jersey
Richard H. Ebright, Ph.D.
Kenneth D. Irvine, Ph.D.
University of Medicine and Dentistry of New Jersey
Ann M. Stock, Ph.D.

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New York

Aaron Diamond AIDS Research Center
Paul D. Bieniasz, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
William R. Jacobs Jr., Ph.D.
Cold Spring Harbor Laboratory
Gregory J. Hannon, Ph.D.
Leemor Joshua-Tor, Ph.D.
Columbia University
Richard Axel, M.D.
Joachim Frank, Ph.D.
Stephen P. Goff, Ph.D.
Iva Greenwald, Ph.D.
Wayne A. Hendrickson, Ph.D.
Oliver Hobert, Ph.D.
Barry Honig, Ph.D.
Thomas M. Jessell, Ph.D.
Eric R. Kandel, M.D.
Steven A. Siegelbaum, Ph.D.
Gary Struhl, Ph.D.
Rafael Yuste, M.D., Ph.D.
Charles S. Zuker, Ph.D.
Cornell University
Shahin Rafii, M.D.
Michelle D. Wang, Ph.D.
Memorial Sloan-Kettering Cancer Center
James P. Allison, Ph.D.
Jonathan Goldberg, Ph.D.
Scott Keeney, Ph.D.
Scott W. Lowe, Ph.D.
Joan Massagué, Ph.D.
Nikola P. Pavletich, Ph.D.
Alexander Y. Rudensky, Ph.D.
Charles L. Sawyers, M.D.
New York University
Ruth Lehmann, Ph.D.
Dan R. Littman, M.D., Ph.D.
Michele Pagano, M.D.
Danny Reinberg, Ph.D.
Eero P. Simoncelli, Ph.D.
The Rockefeller University
Cornelia I. Bargmann, Ph.D.
Günter Blobel, M.D., Ph.D.
Robert B. Darnell, M.D., Ph.D.
Jeffrey M. Friedman, M.D., Ph.D.
Elaine Fuchs, Ph.D.
Nathaniel Heintz, Ph.D.
A. James Hudspeth, M.D., Ph.D.
Roderick MacKinnon, M.D.
Michel C. Nussenzweig, M.D., Ph.D.
Michael E. O’Donnell, Ph.D.
Hermann Steller, Ph.D.
Thomas Tuschl, Ph.D.
Leslie B. Vosshall, Ph.D.

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North Carolina

Duke University
Vann Bennett, M.D., Ph.D.
Erich D. Jarvis, Ph.D.
Robert J. Lefkowitz, M.D.
Paul L. Modrich, Ph.D.
John D. York, Ph.D.
University of North Carolina at Chapel Hill
Yi Zhang, Ph.D.

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Ohio

Cincinnati Children?s Hospital Medical Center
Jeffery D. Molkentin, Ph.D.

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Oklahoma

Oklahoma Medical Research Foundation
Charles T. Esmon, Ph.D.

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Oregon

Oregon Health and Science University
Brian J. Druker, M.D.
Eric Gouaux, Ph.D.
Gail Mandel, Ph.D.
Teresa Nicolson, Ph.D.
University of Oregon
Chris Q. Doe, Ph.D.

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Pennsylvania

The Children’s Hospital of Philadelphia
Katherine A. High, M.D.
University of Pennsylvania
Nancy M. Bonini, Ph.D.
Vivian G. Cheung, M.D.
Gideon Dreyfuss, Ph.D.
Zhe Lu, M.D., Ph.D.
Amita Sehgal, Ph.D.
M. Celeste Simon, Ph.D.
Gregory D. Van Duyne, Ph.D.

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Tennessee

St. Jude Children’s Research Hospital
Brenda A. Schulman, Ph.D.
Charles J. Sherr, M.D., Ph.D.
Vanderbilt University
Kathleen L. Gould, Ph.D.

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Texas

Baylor College of Medicine
Hugo J. Bellen, D.V.M., Ph.D.
Brendan Lee, M.D., Ph.D.
Huda Y. Zoghbi, M.D.
Texas A&M University
L. René García, Ph.D.
University of Texas at Austin
Tanya T. Paull, Ph.D.
University of Texas Southwestern Medical Center at Dallas
Zhijian “James” Chen, Ph.D.
Nick V. Grishin, Ph.D.
Helen H. Hobbs, M.D.
Lora V. Hooper, Ph.D.
Youxing Jiang, Ph.D.
Beth Levine, M.D.
David J. Mangelsdorf, Ph.D.
Michael K. Rosen, Ph.D.
Joseph S. Takahashi, Ph.D.
Xiaodong Wang, Ph.D.
Masashi Yanagisawa, M.D., Ph.D.
Hongtao Yu, Ph.D.

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Utah

University of Utah
Bradley R. Cairns, Ph.D.
Mario R. Capecchi, Ph.D.
Erik M. Jorgensen, Ph.D.

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Washington

Fred Hutchinson Cancer Research Center
Linda B. Buck, Ph.D.
Adrian R. Ferré-D’Amaré, Ph.D.
Steven Henikoff, Ph.D.
Cecilia B. Moens, Ph.D.
James R. Priess, Ph.D.
University of Washington
David Baker, Ph.D.
Michael J. Bevan, Ph.D.
Evan E. Eichler, Ph.D.
Stanley Fields, Ph.D.
Randall T. Moon, Ph.D.
Richard D. Palmiter, Ph.D.
Fred Rieke, Ph.D.
John D. Scott, Ph.D.
Michael N. Shadlen, M.D., Ph.D.
William N. Zagotta, Ph.D.
Ning Zheng, Ph.D.

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Wisconsin

University of Wisconsin—Madison
Paul Ahlquist, Ph.D.
Edwin R. Chapman, Ph.D.
Judith Kimble, Ph.D.

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Early Career Scientists

California

Salk Institute for Biological Studies
Reuben J. Shaw, Ph.D.
Stanford University
Howard Y. Chang, M.D., Ph.D.
Karl Deisseroth, M.D., Ph.D.
Tirin Moore, Ph.D.
University of California, Berkeley
Kristin Scott, Ph.D.
University of California, Davis
Neil Hunter, Ph.D.
University of California, Los Angeles
Mark A. Frye, Ph.D.
Hui Sun, Ph.D.
University of California, San Francisco
Anita Sil, M.D., Ph.D.

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Colorado

University of Colorado
Joaquín M. Espinosa, Ph.D.
Jeffrey S. Kieft, Ph.D.
Rob Knight, Ph.D.

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Connecticut

Yale University
Susan M. Kaech, Ph.D.

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Florida

University of Florida
Martin J. Cohn, Ph.D.

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Illinois

Northwestern University
Luís A. Nunes Amaral, Ph.D.
The University of Chicago
Molly Przeworski, Ph.D.
University of Illinois at Urbana-Champaign
Martin D. Burke, M.D., Ph.D.
Maria Spies, Ph.D.

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Maryland

The Johns Hopkins University
Xinzhong Dong, Ph.D.
Joshua T. Mendell, M.D., Ph.D.
Sinisa Urban, Ph.D.

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Massachusetts

Harvard College, Faculty of Arts and Sciences
Kevin Eggan, Ph.D.
Amy J. Wagers, Ph.D.
Harvard Medical School
Rachel I. Wilson, Ph.D.
Massachusetts General Hospital
Bradley E. Bernstein, M.D., Ph.D.
Konrad Hochedlinger, Ph.D.
Massachusetts Institute of Technology
Michael T. Laub, Ph.D.
Peter W. Reddien, Ph.D.
Aviv Regev, Ph.D.
University of Massachusetts
Marc R. Freeman, Ph.D.
Christopher M. Sassetti, Ph.D.

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Michigan

University of Michigan
Ming Lei, Ph.D.

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Missouri

Stowers Institute for Medical Research
Peter Baumann, Ph.D.

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New York

Columbia University
Eric C. Greene, Ph.D.
Brent R. Stockwell, Ph.D.
Memorial Sloan-Kettering Cancer Center
Jennifer A. Zallen, Ph.D.
New York University
Iannis Aifantis, Ph.D.
Jeremy S. Dasen, Ph.D.
The Rockefeller University
Sean F. Brady, Ph.D.

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North Carolina

Duke University
Kenneth D. Poss, Ph.D.
Ryohei Yasuda, Ph.D.
University of North Carolina at Chapel Hill
James E. Bear, Ph.D.

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Oregon

University of Oregon
Joseph W. Thornton, Ph.D.

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Tennessee

St. Jude Children’s Research Hospital
Michael A. Dyer, Ph.D.

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Texas

University of Texas at Austin
Daniel I. Bolnick, Ph.D.
John B. Wallingford, Ph.D.
University of Texas Southwestern Medical Center at Dallas
Russell A. DeBose-Boyd, Ph.D.

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Washington

Fred Hutchinson Cancer Research Center
Harmit S. Malik, Ph.D.
Toshiyasu Taniguchi, M.D., Ph.D.
University of Washington
Tamir Gonen, Ph.D.

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Janelia Farm Research Campus

Parvez Ahammad, Ph.D.
Junior Fellow
Bruce S. Baker, Ph.D.
Group Leader
Eric Betzig, Ph.D.
Group Leader
Davi Bock, Ph.D.
Fellow
Kristin M. Branson, Ph.D.
Fellow
Sydney Brenner, D.Phil.
Senior Resident Fellow
Gwyneth Card, Ph.D.
Fellow
Dmitri B. Chklovskii, Ph.D.
Group Leader
David A. Clayton, Ph.D.
Laboratory Head
Meng Cui, Ph.D.
Fellow
Winfried Denk, Ph.D.
Senior Fellow
Joshua T. Dudman, Ph.D.
Fellow
Sean R. Eddy, Ph.D.
Group Leader
S.E. Roian Egnor, Ph.D.
Fellow
Mats G.L. Gustafsson, Ph.D.
Group Leader
(Deceased April 17, 2011)
Adam W. Hantman, Ph.D.
Fellow
Timothy D. Harris, Ph.D.
Director, Applied Physics and Instrumentation Group
Harald F. Hess, Ph.D.
Group Leader
Stephen J. Huston, Ph.D.
Junior Fellow
Viren Jain, Ph.D.
Fellow
Vivek Jayaraman, Ph.D.
Group Leader
Na Ji, Ph.D.
Fellow
Alla Y. Karpova, Ph.D.
Group Leader
Philipp J. Keller, Ph.D.
Fellow
Rex A. Kerr, Ph.D.
Fellow
Luke D. Lavis, Ph.D.
Fellow
Albert Lee, Ph.D.
Group Leader
Tzumin Lee, M.D., Ph.D.
Group Leader
Anthony Leonardo, Ph.D.
Group Leader
Loren L. Looger, Ph.D.
Group Leader
Jeffrey C. Magee, Ph.D.
Group Leader
Gabe J. Murphy, Ph.D.
Fellow
Eugene W. Myers, Ph.D.
Group Leader
Eva Pastalkova, Ph.D.
Fellow
Hanchuan Peng, Ph.D.
Senior Computer Scientist
Michael B. Reiser, Ph.D.
Group Leader
Lynn M. Riddiford, Ph.D.
Senior Resident Fellow
Dmitry Rinberg, Ph.D.
Fellow
Elena Rivas, Ph.D.
Fellow
Louis K. Scheffer, Ph.D.
Fellow
Charles V. Shank, Ph.D.
Senior Fellow
Julie H. Simpson, Ph.D.
Group Leader
David Stern, Ph.D.
Group Leader
Scott M. Sternson, Ph.D.
Group Leader
Karel Svoboda, Ph.D.
Group Leader
James W. Truman, Ph.D.
Group Leader
Marta Zlatic, Ph.D.
Fellow
Charles S. Zuker, Ph.D.
Senior Fellow

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