Kinases Are Enzymes That Add Phosphate Groups to Substrates

After binding to a substrate protein, the kinase transfers a phosphate group from ATP to the protein, which alters its behavior.

Phosphorylation is a key process involved in regulating cell division. Therefore, cell division depends on the regulation and activity of corresponding kinases.

A substrate fits into an kinase active site where the kinase transfers a phosphate group from ATP to the protein and results in a phosphorylated substrate (no audio).