Viral Outbreak: The Science of Emerging Disease
Lecture 1 – Dengue Fever: Breaking Epidemic Cycles
by Eva Harris, Ph.D.
2010 Infectious Diseases
2009 Biodiversity
2008 Neuroscience
2007 HIV/AIDS
2006 Stem Cells
2006 Evolution
2005 Evolution
2004 Obesity
2003 Cancer/Neuroscience
2002 Genomics/Chemical Genetics
2001 Sex Determination
2000 Biological Clocks
1999 Infectious Diseases
1998 Cardiovascular Diseases
1997 Neuroscience
1995 RNA
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Lecture 1 – Dengue Fever: Breaking Epidemic Cycles
Lecture 2 – The Virus Hunter's Toolkit
Lecture 3 – Fighting Viruses in the Lab and Beyond
Lecture 4 – Solving SARS and Other Viral Mysteries
Discussion – Biology of the Mosquito Vector
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1.
Start of Lecture 1
2.
Welcome by HHMI President Dr. Robert Tjian
3.
Profile of Dr. Eva Harris
4.
Dr. Harris first visited Nicaragua right after college
5.
What is dengue fever?
6.
Video: Managua: Rapid, Unplanned Urbanization
7.
Dengue virus and vectors
8.
Most dengue cases are asymptomatic
9.
Rapid global spread of dengue
10.
Animation: Dengue Fever Re-emergence in the Americas
11.
Multiple types of dengue virus
12.
Causes of dengue re-emergence
13.
The immune response and severe dengue
14.
A broad-based public health research approach
15.
Pediatric cohort study to track dengue epidemics
16.
Cohort study detects symptomatic and asymptomatic infections
17.
Q&A: Would disease severity be worse if infected by all four serotypes?
18.
Q&A: Would a live or a dead vaccine be better?
19.
Q&A: Who funds your research programs?
20.
Q&A: Is global warming helping spread dengue to the United States?
21.
Spread of mosquito vector, spread of dengue
22.
Large-scale mosquito control programs
23.
Video: The Mosquito Life Cycle
24.
Community-based mosquito education strategies
25.
Video: Mosquito Vector Education Program in Nicaragua
26.
Top-down and bottom-up approaches to mosquito control
27.
A community-based mosquito control program
28.
Measuring the effectiveness of community-based programs
29.
Reduction of mosquito vectors by community-based programs
30.
Building sustainable local capacity for vector control
31.
Video: Health Brigades in Managua's Neighborhoods
32.
Video: Mosquito Reggaeton, a Dengue Rap Song
33.
Q&A: Does dengue fever only spread through mosquito vectors?
34.
Q&A: What protects children who are infected but remain asymptomatic?
35.
Q&A: Would putting screens in windows solve the problem?
36.
Q&A: Do dengue symptoms differ between infants and adults?
37.
Q&A: How is dengue coming to the US? We don't use water barrels.
38.
Q&A: Is dengue a rural problem?
39.
Q&A: How do you control larvae if you can't afford to dump water?
40.
Q&A: Q&A: Are elderly people at greater risk from dengue?
41.
Closing remarks by HHMI President Dr. Robert Tjian
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