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The proteins that make up the icosahedral-shaped capsid are shown. The proteins colored red attach to receptors on the host cell.
As of 2015, there are 50 recognized species in the Adenoviridae family. They infect many different hosts including humans and other mammals, birds, fish, reptiles, and amphibians. In humans they cause many common but relatively mild clinical conditions such as pink eye, the common cold, and bronchitis. Like bacteriophages, adenoviruses are used extensively in scientific research. Adenoviruses are also used as vectors in gene therapy.